National Institutes of Health (NIH) Specific Requirements & Advice

New NIH "FORMS-I" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2025
   High-level Grant Application Form Change Summary: FORMS-I
   Updates to Training Grant Applications

Simplified Review Framework for NIH Research Project Grant Applications - Update and Implementation Plans -- effective Jan 25, 2025
Simplifying Review of Research Project Grant Applications web page

Implementation of Revisions to the NIH and AHRQ Fellowship Application and Review Process -- effective Jan 25, 2025
  Revisions to the NIH Fellowship Application and Review Process web page 

Common Forms for Biographical Sketch and Current and Pending (Other) Support --

  • Effective for applications and Research Performance Progress Reports (RPPRs) submitted on or after May 2025 (target)
  • Will require (1) use of SciENcv to complete forms PLUS (2) additional NIH information collection
  • See Biosketch Format Pages, Instructions and Samples and Biosketch FAQs for updates
  • Watch for informational webinar in late summer/early fall


NIH Grants Process: A Brief Walk-Through for Beginners -- slides and video

About Grants
Includes an interactive 
NIH Grants Process Overview and specific pages from Grants Basics to Pre-Award and Post-Award Processes

Resources and Programs for NIH Grant Applicants
An infographic from the Center for Scientific Review to help clarify the process that highlights institution- and investigator-specific information, including key actions that must be taken well in advance of application submission

Early Stage Investigator (ESI) Policies and Resources

Grants and Funding Glossary

2022-2023 NIH Grants Conference & PreCon Events Season: Session Recordings & Resources

Comparing Popular Research Project Grants: R01, R03 or R21 (NIAID)

NIH AREA (R15) Grants


Office of Extramural Research

PARENT ANNOUNCEMENTS (For Unsolicited or Investigator-Initiated Applications)
Standard Due Dates for Competing Applications

How to Apply - Application Guide
   Changes Coming to NIH Applications and Peer Review in 2025
   Common Forms for Biographical Sketch and Current and Pending (Other) Support
   New NIH "FORMS-I" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2025

Format Attachments

Page Limits
Data Tables for use with Institutional Research Training grant applications, etc.

   MyBibliography User Guide

Note: All Senior/Key Personnel listed on the R&R Profile form must have an eRA Commons ID


Human Subjects Research

Division of Human Subjects Research (DHSR) Resources on Human Subjects, Clinical Trials, and Inclusion
Allowable Costs Related to Participant Inclusion Activities

Basic Experimental Studies Involving Humans (BESH)
NIH has extended flexibilities for registration and results reporting for studies submitted to basic experimental studies with humans (BESH) funding opportunities through September 24, 2024. While BESH investigators are strongly encouraged to register their studies and report summary results to, NIH is continuing to offer the flexibility for investigators to register and report results on alternative publicly available platforms at this time. It is important to note that this flexibility only applies to studies submitted through funding opportunities that are designated as “Basic Experimental Studies with Humans.”

NIH also has updated its Clinical Trial Case Studies to include examples of Basic Experimental Studies Involving Humans (see Cases #9, #14, #40, #41).
[Use the keyword filter to sort and view Case Studies by study type.]


Scientific Data Sharing

Data Management & Sharing Policy Overview
Writing a Data Management & Sharing Plan
Data Management and Sharing Plan Format Page


eRA Commons

New to eRA Commons?
Top 5 eRA  Resources You Should Know




Write Your Application
Samples: Applications, Attachments, and Other Documents

All About Grants Podcasts


Center for Scientific Review - Applicant Resources

  What Happens to Your Application - infographic
  What Happens to Your Application - video
  NIH Peer Review: Grants and Cooperative Agreements
   A ”one-stop explanation of the core values of peer review and the NIH policies that uphold them”

  Assisted Referral Tool (ART) - a tool to recommend a potentially appropriate study section

  Planning and Writing

  Reviewer Guidance on Rigor and Transparency


Apply for a Grant (NIAID)
This comprehensive guide covers all aspects of seeking funding: finding opportunities, interacting with NIH, application preparation, review, and more.
sample applications and summary statements for some funding mechanisms



For other resources, see  RD Digital Library >> NIH -- National Institutes of Health