National Institutes of Health (NIH) Specific Requirements & Advice

Office of Extramural Research

PARENT ANNOUNCEMENTS (For Unsolicited or Investigator-Initiated Applications)

How to Apply - Application Guide

New requirements became effective for due dates on or after January 25, 2022

Format Attachments
Standard Due Dates for Competing Applications

Table of All Instructions, Forms and Formats
Blank biosketch form, data tables for use with Institutional Research Training grant applications, etc.

My Bibliography -- Hints and Help
Resources for New and Early Stage Investigators
Human Subjects Research website
Scientific Data Sharing website
eRA Commons overview



Grant Application Basics
Writing Your Application
Grant Writing Tips Sheets

All About Grants Podcasts

Center for Scientific Review - Applicant Resources

Reviewer Guidance on Rigor and Transparency

Top 100 Peer Review Q&As for NIH Applicants

NIH Peer Review: Grants and Cooperative Agreements
A ”one-stop explanation of the core values of peer review and the NIH policies that uphold them”


Apply for a Grant (NIAID)

This comprehensive guide covers all aspects of seeking funding: finding opportunities, interacting with NIH, application preparation, review, and more. Includes sample applications and summary statements for some funding mechanisms

Comparing Popular Research Project Grants: R01, R03 or R21 (NIAID)

Quick Guide for Grant Applications (NCI)

Common Mistakes in NIH Applications (NINDS)

SBIR/STTR Policy and Grantsmanship Information


Academic Research Enhancement Award [AREA] for Undergraduate-Focused Institutions (R15)

NIH has made some changes to how it will use the R15 mechanism. See NOT-OD-19-015 for details.

Key Points:

  • UNH is eligible ONLY for AREA R15 awards
  • Be sure to use the appropriate AREA FOA for your project ("clinical trial not allowed" or "clinical trial required").
  • Your Grant and Contract Administrator (GCA) in Sponsored Programs Administration (SPA) will upload the now-required institutional eligibility letter when assembling the application package.





Basic Experimental Studies Involving Humans (BESH)

In November 2018, NIH announced the publication of new funding opportunity announcements (FOAs) specifically for Basic Experimental Studies Involving Humans (BESH) (see Open Mike Blog).

Participation in funding opportunities for Basic Experimental Studies with Humans will vary by NIH Institute and Center (IC). Many ICs will continue to accept Basic Experimental Studies with Humans through existing FOAs that accept clinical trials (FOAs designated as Clinical Trial Required or Clinical Trial Optional). It is important to check with a Program Officer to determine the most appropriate FOA for your application.

Need help determining if your research fits within the scope of a BESH FOA?

NIH also has updated its Clinical Trial Case Studies to include examples of Basic Experimental Studies Involving Humans (see Cases #9, #14, #40, #41).
Want to narrow down the list of Case Studies? Try the keyword filter to sort and view Case Studies by study type.


UNH-developed NIH Proposal Development Tools and Resources

  • Comparison of Selected NIH Research Funding Mechanisms
  • Templates – biosketch, current and pending support
  • Hints for NIH Facilities and Other Resources Section, including UNH info for R15 (AREA) applications
  • Whom to Talk to During the NIH Application Process

                and more….