Small Business Grants - SBIR & STTR

NIH Small Business Transition Grant For Early Career Scientists

While most NIH funding supports basic research in university laboratories, the NIH also supports innovative technology development in U.S. small businesses through its SBIR and STTR programs. As technologies transition from academic discovery to small businesses, two common challenges arise, identifying the right team with the right expertise to take the product into a small business, and funding for early-stage technology development. This NOFO seeks to address both challenges simultaneously by having two equally important goals: entrepreneurial mentoring support, and product development support.


Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Grants

Find funding opportunities, proposal preparation hints and assistance, and information about the proposal review process at the sites listed below.



Review Process


Free Proposal Preparation Assistance 

  • I-Trep ProgramContinuing with our mission to promote success in biomedical entrepreneurship, the I-Trep program offers individual one-to-one consulting with experts to assist in the preparation of proposals and the management of awarded SBIR/STTR Grants, webinars, and an intensive summer biomedical entrepreneurship course

    The consultant service is available year-round. Requests are submitted to the I-Trep administrative office where they will be discussed by the Steering Committee. While there is no deadline for the requests, awards will be funded on a first come first served basis.

    If selected, the I-Trep program will put you in contact with an expert to help you with your topic of interest. 
    The I-Trep program will cover the consultation fee (maximum amount $3500). 

    Assistance is available for the following areas:
    1. SBIR/STTR Phase I submission or resubmission
      SBIR/STTR Phase II submission or resubmission
     Accounting for awarded grants
     Compliance assistance for awarded grants

    This intensive biomedical entrepreneurship course is designed to bridge the gap between biomedical researchers and the mainstream customer by providing a practical understanding of what is required to bring products to the marketplace and the roadmap to get there.  This course is free for selected applicants.  Travel and housing are covered for out-of-state participants.

  • NIH SBIR/STTR Policy and Grantsmanship Information
  • US Small Business Administration – SBIR FAQs
  • US Small Business Administration – STTR FAQs

Training and Proposal Preparation Assistance for a Fee

Knowledge Base

The Knowledge Base contains forms, instruction and training material, minutes, policies, tools and other resources to support your research efforts by topic area.