The UNH Research Office is implementing comprehensive grants management and research compliance cloud-based software called Cayuse. One module (Cayuse IRB) is for managing protocols submitted to the UNH Institutional Review Board (IRB) for research involving human subjects. With Cayuse IRB, researchers will be able to streamline IRB submissions and have online access to their IRB protocol records. Some benefits of Cayuse IRB for researchers include:
- Easy to use electronic forms with autofill features
- Ability to submit and certify protocols from their computer or device
- Real-time online submission tracking
- Centralized IRB record management from initial submission through study closure
Please read the following carefully as there will be disruptions in the IRB review process in November and possibly implications for researchers' current studies.
Disruptions in UNH IRB Operations
- The UNH IRB operations will be closed from Monday, November 2 through Friday, November 13, 2020 in order to switch to the new software. During this time, the IRB will not be accepting new applications, requests for modifications, or requests for continuing review.
- The IRB will review on Tuesday, November 3, 2020 applications requiring Full Board review submitted by the deadline of Tuesday, October 20, 2020. The IRB will review on Tuesday, November 17, 2020 applications requiring Full Board review submitted by deadline of Friday, October 30, 2020.
- The UNH IRB operations will resume on Monday, November 16, 2020 using the new Cayuse IRB software.
- Effective this date, researchers with new applications will need to develop them in Cayuse IRB; the IRB staff will not accept new applications submitted via any other means (e.g., email, hard copy).
- Researchers who want to request an extension of the IRB approval for an existing (legacy) study that expires on or after November 16, 2020 and who did not submit the completed continuing review request to the IRB office before Friday, October 30 will need to submit the request via Cayuse IRB on or after November 16, 2020. Researchers should ensure that they do not let their study’s IRB approval lapse. If a study's approval expires, it will be closed in Cayuse. Closed studies cannot be re-opened; researchers will need to submit a new application.
- Researchers who need to request after November 16, 2020 modifications for existing (legacy) studies should contact the IRB office (see below).
Existing (Legacy) Studies with IRB Approval
- Researchers who have existing Exempt* level studies that are ongoing, where the study is anticipated to continue for more than a year or require modifications in the future, should plan to submit a new application in Cayuse IRB after November 16, 2020 to replace the existing study. Doing so will allow researchers to take advantage of the many features of Cayuse IRB to not only have online access to the information about their studies, but also to submit modifications via Cayuse IRB. Once approved, the IRB will close the existing (legacy) IRB protocol.
- Researchers who have Expedited* or Full Board* level studies:
- For those studies in data analysis or interpretation and where there will not be any further data collection or future modifications to the protocol, researchers should submit continuing review requests via Cayuse IRB for the existing (legacy) study.
- For studies that are in the recruitment or data collection stages or where researchers anticipate submitting modifications in the future, they should complete a new application in Cayuse IRB for the study before the study’s current IRB approval expiration date. The IRB will treat it as a new application and give it a new IRB number but, unless the researcher indicates there are changes from the prior version, will perform a cursory review at the previous study’s review level. The new study will receive a new expiration date based on its approval date. At that time, the IRB will close the existing (legacy) study.
*If you are unsure of your study’s protocol review level, please email IRB staff with the IRB protocol number.
Cayuse IRB Training Sessions
The IRB staff are holding training sessions via Zoom during the month of October where they will introduce researchers to the software, walk them through the features and screens, and answer questions. While researchers may find the training helpful in getting familiar with the new platform, attending a session is not a prerequisite to submitting an IRB protocol in the system. Researchers need to pre-register for sessions and the Zoom link will be sent to them the day before the session. Upcoming sessions are as follows:
Session 3: Wednesday, October 14, 2:00 - 4:00 pm
Session 4: Friday, October 16, 10:00 am - noon
Session 5: Wednesday, October 21, 9:00 - 11:00 am ~ register at this link.
Session 6: Friday, October 23, 10:00 am - noon ~ register at this link.
Session 7: Wednesday, October 28, 2:00 - 4:00 pm ~ register at this link.
Session 8: Thursday, October 29, 9:00 - 11:00 am ~ register at this link.