Current Research Projects Modulation of STAT3 activity by STAT5 in triple negative breast cancer Sarah Walker, Ph.D. Targeting PRMT5 to combat cancer drug resistance associated with neuroendocrine differentiation Jingwei Cheng, Ph.D. Proangiogenic Microstructured Hydrogels for Chronic Wound Treatment Linqing Li, Ph.D. Past Research Projects cAMP Signaling in Neuronal Primary Cillia - Xuanmao Chen, Ph.D Design Principles of Microporous Polymeric Scaffolds for Material-Tissue Integration - Kyung Jae Jeong, Ph.D. Development of a Point-of-Care Metabolomic Diagnostic Sensor Towards Identification of Major Depressive Disorder - Jeffrey Halpern, Ph.D. Implantable Sensor Array for In Vivo Real-Time Monitoring of Multiple Neurotransmitters - Edward Song, Ph.D. Neural Pathways Underlying Learning with Nicotine Stimulus - Sergios Charntikov, Ph.D. The critical role of bromodomain proteins TgBDP1 and TgBDP2 in regulating gene expression in the protozoan parasite Toxoplasma gondii - Vicki Jeffers, Ph.D. TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responses - Sherine Elsawa, Ph.D. Past Pilot Projects: Biological DNA based cellular scaffolds - Nate Oldenhuis, Ph.D. Characterization of the gut microbiota-gut-brain axis in adult Bhutanese adults - Maria Carlota Dao, Ph.D. Cryopreservation utilizing antifreeze proteins and polymers - Krisztina Varga, Ph.D. & John Tsavalas, Ph.D. Defining heroin use phenotype - Sergios Charntikov, Ph.D. Development of Gdf-1 as a Ceramide-Regulating Therapeutic for Acute Myeloid Leukemia - Brian Barth, Ph.D. Engineering Pro-angiogenic Biomaterials with Defined Microstructures and Micromechanics to Enhance Wound Healing - Linqing Li, Ph.D. Investigation of an Elastin-Like Polymer Sensing Paradigm for Interleukin-2 - Jeffrey Halpern, Ph.D. Multiscale computational approaches for allosteric targeting of signaling receptors - Harish Vashisth, Ph.D Probing the synergistic effect of inhibitor binding to multiple sites on signaling proteins - Harish Vashisth, Ph.D. & Krisztina Varga, Ph.D. Role of GLI3 in mediating innate immunity - Sherine Elsawa, Ph.D. Role of STAT3 in Advanced Ovarian Cancer - Sarah Walker, Ph.D. The essential bromodomain proteins TgBDP1 and TgBDP2 regulate transcription in Toxoplasma gondii - Vicki Jeffers, Ph.D. The role of PRMT5 in DNA damage repair and alternative RNA splicing regulation in Merkel cell carcinoma - Jingwei Cheng, Ph.D. Toward the inhibitor-bound structures of Regulators of G-protein Signaling Proteins - Krisztina Varga, Ph.D. & Harish Vashisth, Ph.D. PAST Supplement Projects SARS-CoV-2 whole genome sequencing from large-scale campus testing and state-wide communities in NH - W. Kelley Thomas, Ph.D. Targeting STAT3 in Ovarian Cancer - Sarah Walker, Ph.D.