Equipment and Instrumentation
UNH Scientific Instrumentation Inventory
The UNH Scientific Instrumentation Inventory (SII) is a new tool to manage and search the extensive collection of instruments at UNH.
It has been developed by Research Computing and Instrumentation staff to provide a complete and accurate inventory of UNH’s scientific equipment and instruments for many purposes, including:
- identifying potential collaborations, internal and external to UNH
- providing easy access to information needed for research proposals to external sponsors
- determining potential availability/accessibility for broader equipment use on campus
- identifying opportunities to create “Core Facilities”
- identifying opportunities to pool service contract coverage to use institutional funds efficiently
- identifying when equipment/instruments need to be serviced or anticipate replaced
UNH University Instrumentation Center (UIC)
The UIC is a core, University-wide facility dedicated to the advancement of the research and academic missions of UNH. It is open and available to all faculty, staff, and students.
UNH College of Life Sciences and Agriculture (COLSA) Facilities Directory
Laboratories and research facilities mananged by departments with COLSA
Life Sciences Shared Resources @ Dartmouth College
Norris Cotton Cancer Center provides a portfolio of Life Sciences Shared Resources: specialized equipment and instrumentation, as well as services and centralized consultation to support the application of these Shared Resources to research. These resources are available to UNH researchers at the same cost as Dartmouth faculty would pay.
The Shared Resources portfolio includes:
- Clinical Pharmacology
- DartMouse - Speed Congenics
- GeoSpatial Resource
- Immune Monitoring and Flow Cytometry
- Irradiation & Small-Animal Imaging
- Molecular Biology
- Office of Clinical Research
- Pathology Translational Research
- Genetic Constructs
NIH Common Fund Transformative High Resolution Cryo-Electron Microscopy Program Centers
Multiple centers located across the US aim to broaden access to high-resolution cryo-electron microscopy (cryoEM) and tomography (cryoET) for biomedical researchers through instrumentation access at national service centers, and cultivation of a skilled workforce through the development and implementation of cryoEM training material.
3 National cryoEM Service Centers offer usage of state-of-the-art equipment, technical support, and cross-training for the production and analysis of high-resolution data. These offerings are available at no charge for non-profit use, eliminating the high cost barrier usually associated with cryoEM.
4 centers make up the National Network for CryoET to provide the access to advanced instrumentation for cryoET, cryoET specimen preparation, and collection of high-resolution cryoET data as well as cross-training in cryoET methods.
NIH NIGMS National and Regional Resources Program
These centers provide access to state-of-the-art facilities, equipment, technologies, research tools, and software that aren’t generally available to a large number of researchers. To date, the program has established 12 resources that serve the scientific community on a national or multistate regional basis and offer a breadth of technologies.
NIGMS National and Regional Resources (R24) Program
Biomedical National Elemental Imaging Resource (BNEIR) -- Dartmouth College
The Biomedical National Elemental Imaging Resource (BNEIR) will accelerate and simplify access for biomedical researchers to instrumentation, expertise, web-based and in-person training, after-visit support, software and will foster a dynamic community for elemental imaging users.
Dictyostelium Community Resource (DCR) -- Northwestern University
The Dictyostelium Community Resource (DCR) is an integrated resource for investigators using Dictyostelium and related species for biomedical research and training. The DCR integrates two previously separately funded resources, dictyBase (R01GM064426), the model organism database and the Dicty Stock Center (R01GM087371), the strain and materials collection for Dictyostelids, to create a comprehensive community resource.
IDeA National Resource for Quantitative Proteomics -- University of Arkansas for Medical Sciences
The IDeA National Resource for Quantitative Proteomics was created to: 1) Provide state-of-the-art quantitative proteomics services to the IDeA network, 2) Provide outreach opportunities for quantitative proteomics to the IDeA network, and 3) Provide educational opportunities for quantitative proteomics to the IDeA network.
National Glycoscience Resource-CCRC Service and Training -- University of Georgia
The National Resource in Glycoscience will offer service and hands-on training for compositional analysis and detailed structural characterization of all classes of glycoconjugates, including glycoproteins, polysaccharides, and glycolipids, to the greater scientific community.
National Center for Functional Glycomics (NCFG) -- Harvard University
The National Center for Functional Glycomics aims to enable researchers in the under-served area of glycosciences and whose research needs glycoscience expertise, to have continued and improved access to state-of-the-art technologies to advance biomedical research and human health involving protein-glycan interactions and glycan recognition.
National High-Throughput Crystallization Center (HTX) -- Hauptman-Woodward Medical Research Institute
The HTX National Crystallization Center provides unique protein crystallization services for structural biology to academic, government, and non-profit research institutes and industry. The automated crystallization system screens 1,536 crystallization conditions for each protein sample using the microbatch-under-oil method, monitors them with several imaging modalities over a period of six weeks and provides results through notifications, image sets and a final report.
National Resource for Mechanistic Modeling of Cellular Systems -- University of Connecticut, School of Medicine
The National Resource for Mechanistic Modeling of Cellular Systems provides computational modeling, enabled by COPASI and VCell technologies,to offer deep insights into mechanisms by which cells function and the cellular basis of disease.
National User Resource for Biological Accelerator Mass Spectrometry (AMS) -- Lawrence Livermore National Laboratory
The National User Resource for Biological Accelerator Mass Spectrometry (AMS) provides ultra-high sensitivity, quantitative isotopic analysis for biomedical researchers measuring very low-level radioisotopes (primarily 14C). With over 30 years of expertise in the development and application of AMS for biomedical sciences under the BTRR Program (P41GM103483), the User Resource continues to enhance AMS analysis through utilization of new methods, instrumentation, and training for researchers.
NIGMS National and Regional Resources-DNASU -- Arizona State University
DNASU Plasmid Repository Resource is a non-profit, academic-based repository that provides academia, industry and the government with a wide variety of plasmids including specialized vectors, regulatory genetic sequences, and genes from 1,269 organisms, with many complete genome collections, including the first complete human set.
NMR User Program at the National Magnetic Resonance Facility at Madison (NMRFAM) -- University of Wisconsin, Madison
NMRFAM is a unique resource for high-field NMR that leverages mature technologies for scientists, especially those who are not NMR experts, in order solve a wide range of biomedical research problems.
Phenix R24 Resource -- Lawrence Berkeley National Laboratory
Phenix is a software suite that uses reduced data from X-ray diffraction, electron diffraction, neutron diffraction or cryo-EM 3D reconstructions to determine macromolecular structures. The Phenix Resource supports the continued maintenance and optimization of the Phenix code base, the improvements in program usability and integration with other community software resources, and the outreach, training and user support to help grow the community of Phenix users.
Seattle Quant: A Resource for the Skyline Software Ecosystem -- University of Washington
Quantitative mass spectrometry measurements offer a promising alternative to immunological based assays that are the standard for quantitative protein measurements in clinical and basic research laboratories. Critical to these experiments is our software, Skyline and the associated ecosystem of tools, which have been developed to handle the generation of instrument methods and the subsequent analysis of the resulting data.
The Genomic Enzymology Web-Based Resource -- University of Illinois at Urbana-Champaign
The Genomic Enzymology Web-Based Resource integrates three tools to enable the discovery of novel proteins and metabolic pathways. The tool pipeline is comprised of three analysis steps: (1) generation of sequence similarity networks (SSNs) enabling the semi-automated reconstruction of high-quality protein families built around any protein sequence, (2) parallel exploration of the genome neighborhood of a protein family across a diverse set of input genomes to discover functionally linked gene products to infer novel enzymatic functions and metabolic pathways, and (3) determination of metagenome abundance of clusters in the SSNs to discover important targets for functional assignment.