RESEARCH PROJECTS

Current Projects:

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responses- Sherine Elsawa, Ph.D.

The critical role of bromodomain proteins TgBDP1 and TgBDP2 in regulating gene expression in the protozoan parasite Toxoplasma gondii - Vicki Jeffers, Ph.D.

Current Supplements:

SARS-CoV-2 whole genome sequencing from large-scale campus testing and state-wide communities in NH-- W. Kelley Thomas, Ph.D.

Targeting STAT3 in Ovarian Cancer - Sarah Walker, Ph.D.

Current Pilot Projects:

The role of PRMT5 in DNA damage repair and alternative RNA splicing regulation in Merkel cell carcinoma - Jingwei Cheng, Ph.D.

Characterization of the gut microbiota-gut-brain axis in adult Bhutanese adults - Maria Carlota Dao, Ph.D.

Biological DNA based cellular scaffolds - Nate Oldenhuis, Ph.D.

Cryopreservation utilizing antifreeze proteins and polymers - Krisztina Varga, Ph.D. & John Tsavalas, Ph.D.

Past Projects:

Neural Pathways Underlying Learning with Nicotine Stimulus - Sergios Charntikov, Ph.D.

Development of a Point-of-Care Metabolomic Diagnostic Sensor Towards Identification of Major Depressive Disorder - Jeffrey Halpern, Ph.D.

Implantable Sensor Array for In Vivo Real-Time Monitoring of Multiple Neurotransmitters - Edward Song, Ph.D.

Design Principles of Microporous Polymeric Scaffolds for Material-Tissue Integration - Kyung Jae Jeong, Ph.D.

 cAMP Signaling in Neuronal Primary Cillia - Xuanmao Chen, Ph.D

 

Past Pilot Projects:

Multiscale computational approaches for allosteric targeting of signaling receptors -Harish Vashisth, Ph.D

Role of GLI3 in mediating innate immunity- Sherine Elsawa, Ph.D.

Toward the inhibitor-bound structures of Regulators of G-protein Signaling Proteins- Krisztina Varga, Ph.D. & Harish Vashisth, Ph.D.

The essential bromodomain proteins TgBDP1 and TgBDP2 regulate transcription in Toxoplasma gondii - Vicki Jeffers, Ph.D.  

Development of Gdf-1 as a Ceramide-Regulating Therapeutic for Acute Myeloid Leukemia - Brian Barth, Ph.D.

Defining heroin use phenotype - Sergios Charntikov, Ph.D.

Investigation of an Elastin-Like Polymer Sensing Paradigm for Interleukin-2 - Jeffrey Halpern, Ph.D.

Probing the synergistic effect of inhibitor binding to multiple sites on signaling proteins - Harish Vashisth, Ph.D. & Krisztina Varga

Role of STAT3 in Advanced Ovarian Cancer - Sarah Walker, Ph.D.