RESEARCH PROJECTS

CURRENT PROJECTS:

  • TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responses- Sherine Elsawa, Ph.D.

  • The critical role of bromodomain proteins TgBDP1 and TgBDP2 in regulating gene expression in the protozoan parasite Toxoplasma gondii - Vicki Jeffers, Ph.D.

CURRENT Supplements:

  • SARS-CoV-2 whole genome sequencing from large-scale campus testing and state-wide communities in NH-- W. Kelley Thomas, Ph.D.

  • Targeting STAT3 in Ovarian Cancer - Sarah Walker, Ph.D.

Current PILOT PROJECTS:

  • The role of PRMT5 in DNA damage repair and alternative RNA splicing regulation in Merkel cell carcinoma - Jingwei Cheng, Ph.D.

  • Characterization of the gut microbiota-gut-brain axis in adult Bhutanese adults - Maria Carlota Dao, Ph.D.

  • Biological DNA based cellular scaffolds - Nate Oldenhuis, Ph.D.

  • Cryopreservation utilizing antifreeze proteins and polymers - Krisztina Varga, Ph.D. & John Tsavalas, Ph.D.

 

PAST PROJECTS:

  • Neural Pathways Underlying Learning with Nicotine Stimulus - Sergios Charntikov, Ph.D.

  • Development of a Point-of-Care Metabolomic Diagnostic Sensor Towards Identification of Major Depressive Disorder - Jeffrey Halpern, Ph.D.

  • Implantable Sensor Array for In Vivo Real-Time Monitoring of Multiple Neurotransmitters - Edward Song, Ph.D.

  • Design Principles of Microporous Polymeric Scaffolds for Material-Tissue Integration - Kyung Jae Jeong, Ph.D.

  •  cAMP Signaling in Neuronal Primary Cillia - Xuanmao Chen, Ph.D

 

PAST PILOT PROJECTS:

  • Multiscale computational approaches for allosteric targeting of signaling receptors -Harish Vashisth, Ph.D

  • Role of GLI3 in mediating innate immunity- Sherine Elsawa, Ph.D.

  • Toward the inhibitor-bound structures of Regulators of G-protein Signaling Proteins- Krisztina Varga, Ph.D. & Harish Vashisth, Ph.D.

  • The essential bromodomain proteins TgBDP1 and TgBDP2 regulate transcription in Toxoplasma gondii - Vicki Jeffers, Ph.D.  

  • Development of Gdf-1 as a Ceramide-Regulating Therapeutic for Acute Myeloid Leukemia - Brian Barth, Ph.D.

  • Defining heroin use phenotype - Sergios Charntikov, Ph.D.

  • Investigation of an Elastin-Like Polymer Sensing Paradigm for Interleukin-2 - Jeffrey Halpern, Ph.D.

  • Probing the synergistic effect of inhibitor binding to multiple sites on signaling proteins - Harish Vashisth, Ph.D. & Krisztina Varga

  • Role of STAT3 in Advanced Ovarian Cancer - Sarah Walker, Ph.D.