| Biochemistry |
BCHM 600 - Field Experience
Credits:
1.00 to 4.00
A supervised experience providing the opportunity to apply
academic experience in settings associated with future
professional employment and/or related graduate
opportunities. Must be approved by a faculty advisor
selected by the student. May be repeated to a maximum of 8
credit hours. Prereq: permission. Cr/F.
BCHM 600W - Field Experience
Credits:
1.00 to 4.00
See description for BCHM 600. Cr/F. Writing intensive.
BCHM 658 - General Biochemistry
Credits:
3.00
A comprehensive, introductory course emphasizing the
cellular metabolism and the structure and function of
proteins, nucleic acids, carbohydrates, and lipids. Prereq:
BIOL 411, CHEM 545-546, CHEM 547-548, or CHEM 651-652.
Coreq: BCHM 659 (except BCHM majors who are encouraged to
take BCHM 755).
Co-requisites:
BCHM 659
BCHM 659 - General Biochemistry Laboratory
Credits:
2.00
Structured laboratory experiments that provide training in
analytical and preparative techniques fundamental to
modern biochemistry and molecular biology. Coreq: BCHM 658
(except for BCHM majors who are encouraged to take BCHM 755
instead of BCHM 659). Special fee.
Co-requisites:
BCHM 658
BCHM 702 - Endocrinology
Credits:
4.00
Biochemical and molecular structure and function of
vertebrate endocrine systems. Influence of endocrine
system on the physiology of vertebrates, with special
reference to mammals. Current investigations of the
endocrine system as a regulator and integrator of body
functions including such systems as growth, reproduction,
metabolism, differentiation, and behavior. (Also offered
as ANSC 702.) Prereq: BCHM 658 or 751;/or permission.
Special fee.
BCHM 702W - Endocrinology
Credits:
4.00
See description for BCHM 702. Special fee. Writing
intensive.
BCHM 711 - Genomics and Bioinformatics
Credits:
4.00
The methods, applications, and implications of
genomics--the analysis of whole genomes. Microbial, plant
and animal genomics are addressed, as well as medical,
ethical and legal implications. The lab provides exposure
and experience of a range of bioinformatics approaches--the
computer applications used in genome analysis. Prereq: BIOL
604. (Also offered as GEN 711 and MICR 711.) Lab.
BCHM 750 - Physical Biochemistry
Credits:
3.00
Structure, interactions, and physical-chemical properties
of biomolecules. Thermodynamic, kinetic, and
spectroscopic methods for the study of proteins and nucleic
acids. Prereq: 2 semesters organic chemistry, 1 semester of
calculus;/ or permission.
BCHM 751 - Principles of Biochemistry
Credits:
4.00
In-depth survey of biochemistry: macromolecular structure;
structure and function of proteins, nucleic acids,
carbohydrates, and lipids. Prereq: CHEM 657-658 or CHEM
651-652 or CHEM 545 and 546 and BCHM 658-659;/ or permission
BCHM 752 - Principles of Biochemistry
Credits:
4.00
Continuation of in-depth survey of biochemistry:
metabolism of amino acids, nucleotides, carbohydrates and
lipids; macromolecules synthesis and regulation; molecular
biology of the eukaryotic cell. Prereq: BCHM 751 or
permission.
BCHM 754 - Laboratory in Biochemistry and Molecular Biology of Nucleic Acids
Credits:
5.00
Application of modern techniques to the analysis of
biomolecules, with an emphasis on nucleic acids; includes
DNA isolation and analysis, cloning, sequencing, and
analysis of gene products. No credit if credit has been
received for MICR 704. Prereq: BCHM 658/659; 751; or
permission. (Also offered as PBIO 754 and GEN 754.) Special
fee. (Not offered every year.) Writing intensive.
BCHM 755 - Laboratory in Biochemistry and Molecular Biology
Credits:
5.00
Application of modern techniques to the characterization
and purification of biomolecules, with an emphasis on
proteins and nucleic acids; analysis of enzyme kinetics;
and basic techniques used in molecular biology. (Majors
anticipating taking BCHM 799 should take this course in
their junior year.) Prereq: BCHM 751-752;/ or permission.
BCHM 752 may be taken concurrently with BCHM 755. Special
fee. Writing intensive.
BCHM #761 - Cell Signaling Transduction in Health and Disease
Credits:
3.00
Signal transduction and the regulation of metabolism, cell
growth, and cellular activation. Emphasis is on the
molecular basis of cellular communication, sensory signal
transduction and cancer. Prereq: BCHM 751 or 658;/ or
permission.
BCHM 763 - Biochemistry of Cancer
Credits:
3.00
Molecular mechanisms of viral and chemical carcinogenesis;
role of oncogenes in normal cell growth, development, and
differentiation. Biochemical basis of cancer chemotherapy.
Prereq: BCHM 658 or 751;/or permission.
BCHM 766 - Environmental Genomics
Credits:
4.00
The field of environmental genomics uses existing and
developing high throughput genomic-scale technologies to
investigate ecological and evoluntionary theory, and so
provides a more complete understanding of how organisms
respond to environmental change at the molecular genetic
level. Course covers an array of systems involved in this
emerging field, with the central aim of understanding the
effects of environmental change on genome structure, gene
expression, and adaptive evolutionary change. Information
is derived from the primary literature in the field and
covers practical and technical concepts as well as the
underlying theoretical basis for the major research themes.
Prereq: BIOL 604;/ or permission. (Also offered as GEN 766.)
BCHM 771 - Molecular Genetics
Credits:
4.00
Structure, organization, replication dynamics, and
expression of genetic information in eukaryotes. Focus on
molecular genetic mechanisms of gene expression and its
control; molecular genetics methods; molecular genetic
control of cell division and differentiation during
development. Prereq: BCHM 658 or 751; BIOL 604;/or
permission. (Also offered as GEN 771.)
BCHM 782 - Developmental Genetics
Credits:
3.00
The molecular genetic basis of metazoan development.
Focuses on how genes direct the process of development and
how this problem is analyzed in model organisms using
molecular genetic approaches. Topics include: control of
cell division, maternal factors, cell-cell interactions,
and differential gene expression. Prereq: BIOL 604; BCHM
658 or 751. (Also offered as GEN 782.) Not offered every yea
BCHM 790 - Current Topics in Biomedicine
Credits:
4.00
The dramatic advances in molecular biology and
biochemistry during the last two decades have led to
explosive growth in the accumulation of biomedical
knowledge. To "discover" the literature is an essential
element of training in any molecular discipline in biology.
The first phase of the course will cover the use of
literature search tools, and how to read scientific papers,
write a review and make presentations effectively. The bulk
of the time will be spent on current topics in biomedicine
selected by the class. With guidance from the instructor,
the class will derive reading lists, discuss the
literature, and then write short essays on each topic.
Participants will also prepare a "term" project for
audiovisual presentation to the class in the final two
weeks. Prereq: BIOL 605 or instructor permission. Writing
intensive.
BCHM 794 - Protein Structure and Function
Credits:
4.00
Analysis of how the three-dimensional architecture of
soluble and membrane proteins contributes to their
biochemical function. Topics include methods for
determining the structure of proteins, protein folding,
protein targeting, and mechanisms of enzyme catalysis.
Computer resources will be used for protein modeling and
structural prediction. Prereq: BCHM 658 or 751.
BCHM 795 - Investigations
Credits:
1.00 to 4.00
Independent study in various areas including but not
limited to: genetics, signal transduction, gene
regulation, molecular evolution, biochemistry of cancer,
biophysics of macromolecules, endocrinology, and
glycobiology. May include readings, laboratory work,
organized seminars and conferences.Prereq: permission. Not
more than 4 total credit hours can be applied to BCHM or
major electives.
BCHM 795W - Investigations
Credits:
1.00 to 4.00
See description for BCHM 795. Writing intensive.
BCHM 799 - Senior Thesis
Credits:
1.00 to 4.00
Research in biochemistry and molecular biology for senior
majors. Topics may include: developmental genetics; signal
transduction; gene regulation; molecular evolution;
biochemistry of cancer; biophysics of macromolecules;
endocrinology; glycobiology. May be repeated to a maximum
of 4 credits. Prereq: BCHM 659 or 755; permission. Writing
intensive.
BCHM 799H - Honors Senior Thesis
Credits:
1.00 to 4.00
See description for BCHM 799. Writing intensive.