| Biochemistry |
BCHM 600 - Field Experience
Credits:
1.00 to 4.00
A supervised experience providing the opportunity to apply
academic experience in settings associated with future
professional employment and/or related graduate
opportunities. Must be approved by a faculty advisor
selected by the student. May be repeated to a maximum
of 8 credit hours. Prereq: permission. CR/F.
BCHM 658 - General Biochemistry
Credits:
3.00
A comprehensive, introductory course emphasizing the
cellular metabolism and the structure and function of
proteins, nucleic acids, carbohydrates, and lipids.
Prereq: BIOL 411, CHEM 545-546, CHEM 547-548, or
CHEM 651-652. Coreq: BCHM 659 (except BCHM majors who are
encouraged to take BCHM 755).
Co-requisites:
BCHM 659
BCHM 659 - General Biochemistry Laboratory
Credits:
2.00
Structured laboratory experiments that provide training in
analytical and preparative techniques fundamental to modern
biochemistry and molecular biology. Coreq: BCHM 658 (except
for BCHM majors who are encouraged to take BCHM 755 instead
of BCHM 659). Special fee.
Co-requisites:
BCHM 658
BCHM 702 - Endocrinology
Credits:
4.00
Biochemical and molecular structure and function of
vertebrate endocrine systems. Influence of endocrine system
on the physiology of vertebrates, with special reference to
mammals. Current investigations of the endocrine system as a
regulator and integrator of body functions including such
systems as growth, reproduction, metabolism,
differentiation, and behavior. (Also offered as ANSC 702.)
Prereq: BCHM 658 or 751;/or permission. Special fee.
BCHM 711 - Genomics and Bioinformatics
Credits:
4.00
The methods, applications, and implications of genomics--
the analysis of whole genomes. Microbial, plant and animal
genomics are addressed, as well as medical, ethical and
legal implications. The lab provides exposure and experience
of a range of bioinformatics approaches--the computer
applications used in genome analysis. Prereq: BIOL 604.
(Also offered as GEN 711 and MICR 711.) Lab.
BCHM 750 - Physical Biochemistry
Credits:
3.00
Structure, interactions, and physical-chemical properties
of biomolecules. Thermodynamic, kinetic, and spectroscopic
methods for the study of proteins and nucleic acids.
Prereq: BCHM 751; or permission.
BCHM 751 - Principles of Biochemistry
Credits:
4.00
In-depth survey of biochemistry; macromolecular structure;
metabolism of proteins, nucleic acids, carbohydrates, and
lipids; molecular biology of DNA, RNA, and protein synthesis
and regulation. Prereq: CHEM 547-548 or CHEM 651-652 or
CHEM 545 and 546;/or permission.
BCHM 752 - Principles of Biochemistry
Credits:
4.00
In-depth survey of biochemistry; macromolecular structure;
metabolism of proteins, nucleic acids, carbohydrates, and
lipids; molecular biology of DNA, RNA, and protein synthesis
and regulation. Prereq: CHEM 547-548 or CHEM 651-652 or
CHEM 545 and 546;/or permission.
BCHM 754 - Laboratory in Biochemistry and Molecular Biology of Nucleic Acids
Credits:
5.00
Application of modern techniques to the analysis of
biomolecules, with an emphasis on nucleic acids; includes
DNA isolation and analysis, cloning, sequencing, and
analysis of gene products. No credit if credit has been
received for MICR 704. Prereq: BCHM 658/659; 751; or
permission. (Also offered as PBIO 754 and GEN 754.) Special
fee. (Not offered every year.) Writing intensive.
BCHM 755 - Laboratory in Biochemistry and Molecular Biology
Credits:
5.00
Application of modern techniques to the characterization
and purification of biomolecules, with an emphasis on
proteins and nucleic acids; analysis of enzyme kinetics; and
basic techniques used in molecular biology. (Majors
anticipating taking BCHM 799 should take this course in
their junior year.) Prereq: BCHM 751-752;/ or permission.
BCHM 752 may be taken concurrently with BCHM 775. Special
fee. Writing intensive.
BCHM 760 - Cellular Signaling Processes
Credits:
4.00
Signal transduction and the regulation of metabolism, cell
growth, and cellular activation; molecular basis of cellular
communication. Prereq: BCHM 658 or 751;/or permission.
Writing Intensive.
BCHM 763 - Biochemistry of Cancer
Credits:
3.00
Molecular mechanisms of viral and chemical carcinogenesis;
role of oncogenes in normal cell growth, development, and
differentiation. Biochemical basis of cancer chemotherapy.
Prereq: BCHM 658 or 751;/or permission.
BCHM 764 - Membrane Biochemistry
Credits:
3.00
Structure and biogenesis of membranes and membrane proteins.
Transport across the membrane and bioenergetic membranes,
mechanisms of protein targeting, processing, and
trafficking. Prereq: BCHM 658 or 751;/or permission.
BCHM 766 - Environmental Genomics
Credits:
4.00
The field of environmental genomics uses existing and
developing high throughput genomic-scale technologies to
investigate ecological and evoluntionary theory, and so
provides a more complete understanding of how organisms
respond to environmental change at the molecular genetic
level. Course covers an array of systems involved in this
emerging field, with the central aim of understanding the
effects of environmental change on genome structure, gene
expression, and adaptive evolutionary change. Information is
derived from the primary literature in the field and covers
practical and technical concepts as well as the underlying
theoretical basis for the major research themes. Prereq:
BIOL 604;/ or permission. (Also offered as GEN 766.)
BCHM 771 - Molecular Genetics
Credits:
4.00
Structure, organization, replication dynamics, and
expression of genetic information in eukaryotes. Focus on
molecular genetic mechanisms of gene expression and its
control; molecular genetics methods; molecular genetic
control of cell division and differentiation during
development. Prereq: BCHM 658 or 751; BIOL 604;/or
permission. (Also offered as GEN 771.)
BCHM 782 - Developmental Genetics
Credits:
3.00
The molecular genetic basis of metazoan development.
Focuses on how genes direct the process of development and
how this problem is analyzed in model organisms using
molecular genetic approaches. Topics include: control of
cell division, maternal factors, cell-cell interactions, and
differential gene expression. Prereq: BIOL 604; BCHM 658 or
751. (Also offered as GEN 782.) Not offered every year.
BCHM 794 - Protein Structure and Function
Credits:
3.00
Analysis of how the three-dimensional architecture of
proteins and enzymes contributes to their biochemical
function. Topics include methods for determining the
structure of proteins, protein folding, intermolecular
interactions of proteins, mechanisms of enzyme catalysis,
enzyme kinetics, protein evolution, and biosynthesis.
Prereq: BCHM 658 or 751.
BCHM 795 - Investigations
Credits:
1.00 to 4.00
Independent study in various areas including but not limited
to: genetics, signal transduction, gene regulation,
molecular evolution, biochemistry of cancer, biophysics of
macromolecules, endocrinology, and teaching experience.
Prereq: permission. Not more than 4 total credit hours can
be applied to BCHM or major electives.
BCHM 799 - Senior Thesis
Credits:
1.00 to 4.00
Research in biochemistry and molecular biology for senior
majors. Developmental genetics; signal transduction; gene
regulation; molecular evolution; biochemistry of cancer;
biophysics of macromolecules; endocrinology; glycobiology.
May be repeated to a maximum of 4 credits. Prereq: BCHM 659
or 755; permission. Writing intensive.
BCHM 799H - Honors Senior Thesis
Credits:
1.00 to 4.00
See description for BCHM 799. Writing intensive.