Kinetic and dynamic studies can be done on nearly all NMR active elements. Both 1-D and 2-D experiments are now offered including: INEPT, DEPT, carbon-carbon coupling detection (INADEQUATE), COSY, NOESY, ROESY, TOCSY, HMQC/HSQC/HMBC, and many others.
This instrument uses a double beam, double out-of-plane Littrow monochromator and dual double-sided gratings with up to 3 sources. Detection in the UV/Vis range is with a high performance R928 photomultiplier tube and, in the NIR, with a low noise, electrothermally-controlled PbS photocell. Spectral bandwidths from 0.01 - 5.00 nm (UV/Vis) and 0.04 - 20.0 nm (NIR) are possible. Signal averaging is available from 0.033 to 999 seconds and scan rates up to 2000 nm/min (UV/VIS) and 8000 nm/min (NIR).
The Thermo Nicolet iS10 FT-IR is a general-purpose, Windows XP controlled instrument designed for easy operation using the OMNIC 8 software. The resolution of the spectrometer is 0.4 cm-1, and the spectral range is 7800 to 350 cm. The sample chamber and optics are purged with air with a dew point of -95oF. We also have a diamond ATR accessory with a spectral range cutoff of 525 cm-1 for use with most samples.
The system is designed around a 127 mm mean radius hemispherical analyzer, which is equipped with a triple channeltron detection system for improved sensitivity. By using a magnetic immersion lens, high sensitivity is apparent on small analysis areas. A standard feature is XPS Imaging, which goes down to the 30 um level. The charge neutralization system allows high resolution spectra to be obtained from insulating materials such as polymers using either the standard Mg/Al source or the Al monochromatic source.
The unit has a Mac G4 host computer, and most instrument functions are computer controlled. The unit has two lasers for exciting fluorochromes: an argon laser, which emits sapphire-colored light at 488 nm, and a red diode laser emitting light at 635 nm. This unit is best suited for the analysis of aqueous suspensions of cells or particles with diameters between 1 and 50 um (microns).