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OEHS Directory

Radionuclide Fact Sheet

PHOSPHORUS - 33

Symbol: 33P

States/Forms: Soluble

Physical Characteristics

  • Radioactive Half Life (T½): 25 days
  • Decay Type: Beta-)
  • Maximum Energy Emission: 0.249 MeV
  • Maximum Range in Air: 49 cm
  • Maximum Range in Water/Tissue: 0.06 cm
  • Maximum Range in Plexiglas or Lucite: 0.05 cm

Hazard Category

  • A Level (High Hazard): >1 Ci
  • B Level (Moderate Hazard): >20 mCi to 1 Ci
  • C Level (Low Hazard): 0.1 mCi to 20 mCi

Radiological Characteristics

  • 40% of beta particle energy transmitted through dead layer of skin.
  • Critical organs: Bone marrow – 30%; Body tissues – 70%
  • Routes of intake: Ingestion, inhalation, puncture, wound, skin contamination (absorption).
  • Internal exposure and contamination: Primary radiological concerns with 33P.
  • External exposure: Minimal concern for 33P.

Dosimetry

  • Film badges and dosimeter rings are not appropriate for monitoring 33P exposure.

Bioassay Requirements

  • Urinalysis may be required after spills or incidents of contamination.

External Radiation Hazards and Shielding

  • There is minimal external hazard with 33P, i.e. the glass vial containing the 33P provides sufficient shielding from the beta particles, however lucite or plexiglas may be used as shielding.  If the skin is uniformly contaminated with 33P, 1 microcurie/cm2 (Ci/cm2) will deliver a dose of 3200 miilirems per hour (mrems/hr) to the basal skin cells.

Hazards if Internally Deposited

ALI (Annual Limit of Intake):

  • 4000 μCi – by ingestion
  • 6000 μCi – by inhalation

DAC (Derived Air Concentration):

  • 3 x 10-6 μCi/mL

Survey Instrumentation

  • A Geiger-Muller survey detector with a pancake/frisker probe can be used to detect 33P.  The counting efficiency for 33P is approximately 6%.
  • Liquid scintillation counters should be used to detect removable surface 33P contamination using smears or swabs.

Problems and Precautions

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