Vernon N. Reinhold
Research Professor
Bioanalytical Chemistry
Department of Chemistry
University of New Hampshire
Durham, NH 03824 U.S.A.
Phone: 603-862-2527
Fax: 603-862-4278
vernon.reinhold@unh.edu
Education and Achievements
- B.S., 1959, University of New Hampshire
- M.S., 1961, University of New Hampshire
- Ph.D., 1965, University of Vermont
- Atomic Energy Commission Fellow, 1966-1968, Brookhaven National Laboratories
- Helen Hay Whitney Fellow, 1969-1972, Joint Appointment MIT-Harvard University
- Research Associate, MIT, 1973-1975, DRR Mass Spectrometry Facility
- Lecturer in Biological Chemistry and Molecular Biology, 1976-1996, Harvard Medical School
- Director Mass Spectrometry Facility, 1985-1996, Harvard School of Public Health
- Professor in Microbiology, 1996-1998, Boston University Medical School
- Adjunct Professor in Microbiology, 1998-present, Boston University Medical School
- Research Professor in Chemistry & Biochemistry, 1998-present, University of New Hampshire
- Director, Center for Structural Biology, 2001-present, University of New Hampshire
Research Interests
Structural glycobiology; glycomic functional relationships in eukaryotic cells.
http://glycome.unh.edu
Group Members
Research Professor: Vernon N. Reinhold
Staff: Current Reinhold group member profiles can be viewed at: http://glycome.unh.edu/csb/people/people.htm.
Recent Publications
Tong, Y., Arking, D., Reinhold, B.B., Reinhold, V.N., Stein, D.C., (2001) Characterization of Lipooligosaccharide Structures Found in Neisseria gonorrhoeae PID2. J. Bacteriology, (accepted, August, 2001).
Yohe, H.C., Wallace, P.K. Berenson, C.S., Ye, S., Reinhold, B.R., Reinhold, V.N. (2001). The Major Gangliosides of Human Peripheral Blood Monocytes/macrophages; Absence of Ganglio Series Structures. Glycobiology, 11, 831-841.
Duk, M., Reinhold, B.B., Reinhold, V.N., Kusnierz-Alejska, G., Lisowska, E. (2001). The Structure of a Neutral Glycosphingolipid Recognized by Human Antibodies in Polyagglutinable Erythrocytes of Rare NOR Phenotype. J. Biol. Chem., (in press, Nov. 2001).
Kamath, A.B., Wang, L., Das, H., Li, L., Reinhold, V.N., Bukowski, J.F. (2003) Antigens in tea-beverage prime human Vg2Vd2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses. Proc. Nat. Acad. Sci., 100, 6009-6014. (May 13, 2003).
Zhu, S., Hanneman, A.J., Reinhold, V.N., Spence, A.M., Schachter, H. (2004) Caenorhabditis elegans triple mutant lacking UDP-N-acetyl-D-glycosamine::a-3-D-mannoside b1,2-N-acetylglucosaminyltransferase I. Biochem. J., 382, (2), 995-1001.
Berenson CS, Sayles KB, Huang J, Reinhold VN, Garlipp MA, Yohe HC "Nontypeable Haemophilus influenzae-binding gangliosides of human respiratory (HEp-2) cells have a requisite lacto/neolacto core structure", (2005) FEMS Immunol and Medical Microbiol. 44, 250-261.
Geiser, H. Silvescu, C.I., and Reinhold, V.N. (2005) The Developing Field of Glycoproteomics. In: Separation Methods in Proteomics. Gary Smejkal, Editor. Publisher, Marcel-Dekker Inc. New York City.
Hanneman, A.J., and Reinhold, V.N. (2005) Oligosaccharide Analysis by Mass Spectrometry, Encyclopedia of Biological Chemistry, 3, 155-160.
Lapadula, A. J., Hatcher, P. J., Zhang, H., and Reinhold, V. N. (2005) Congruent Strategies for Carbohydrate Sequencing III. OSCAR: An Algorithm for Assigning Oligosaccharide Topology from MSn Data; Analytical Chemistry 77, (Submitted 4/2005-third report in this series).
Ashline, D., Sing, S., Hanneman, A., and Reinhold, V. N. (2005) Congruent Strategies for Carbohydrate Sequencing I. Mining Structural Details by MSn. Analytical Chemistry 77, (Submitted 4/2005-first report in this series).
Zhang, H., Singh, S., and Reinhold, V. N. (2005) Congruent Strategies for Carbohydrate Sequencing II. FragLib: An MSn Spectral Library. Analytical Chemistry 77, (Submitted 4/2005-second report in this series).
Zavareh, Reza Beheshti, Ashline, David, and Reinhold, Vern N. et al, Inhibition of the Sodium/Potassium ATPase Impairs N -Glycan Expression and Function, Cancer Res 2008; 68 (16) Aug. 15, 2008.
Prien, Justin M., Ashline, David J., Lapadula, Anthony J. and Reinhold, Vernon N. et al, Differentiating N-linked glycan structure isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometry, Glycobiology, 18, 5, 2008, p. 353.
Bleckmann, Christina, Reinhold, Vernon et al, Glycomic Anlysis of N-Linked Carbohydrate Epitopes from CD24 of Mouse Brain, J. Proteome Res, Article ASAP, Dec. 7, 2008.