Harish Vashisth
Harish Vashisth, Assistant Professor
Education
Computational Biophysics, Biomolecular Simulations, Molecular Transport, Cell Signaling via Membrane Proteins
Harish Vashisth and Cameron F. Abrams, “All-atom structural models of insulin binding to the insulin receptor in the presence of a tandem hormone-binding element,” Proteins 81:1017-1030 (2013). (Featured on Journal Cover)
Harish Vashisth, Georgios Skiniotis, and Charles L. Brooks III, “Enhanced sampling and overfitting analyses in structural refinement of nucleic acids into electron microscopy maps,” J. Phys. Chem. B 117:3738-3746 (2013).
Harish Vashisth and Charles L. Brooks III, “Conformational sampling of maltose-transporter components in Cartesian collective variables is governed by the low-frequency normal modes,” J. Phys. Chem. Lett. 3:3379-3384 (2012)
Harish Vashisth, Georgios Skiniotis, and Charles L. Brooks III, “Using enhanced sampling and structural restraints to refine atomic structures into low-resolution electron microscopy maps,” Structure 20:1453-1462 (2012) Featured by Journal as Top 20 Most-read Papers
Harish Vashisth, Luca Maragliano, and Cameron F. Abrams, “DFG-flip in the insulin receptor kinase is facilitated by a helical intermediate state of the activation loop,” Biophys. J. 102:1979-1987 (2012).
Bethany S. Strunk, Cherisse Rae Loucks, Min Su, Harish Vashisth, Shanshan Cheng, Justin Schilling, Charles L. Brooks III, Katrin Karbstein, and Georgios Skiniotis, “Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates,” Science 333:1449-1453 (2011). (Highlighted in News and Views, Nat. Struct. Mol. Biol.)
Harish Vashisth and Cameron F. Abrams, “All-atom structural models for complexes of insulinlike growth factors IGF1 and IGF2 with their cognate receptor,” J. Mol. Biol. 400:645-658 (2010).
Harish Vashisth and Cameron F. Abrams, “Docking of insulin to a structurally equilibrated insulin receptor ectodomain,” Proteins 78:1531-1543 (2010). (Featured on Journal Cover)
Harish Vashisth and Cameron F. Abrams, “Ligand escape pathways and (un)binding free energy calculations for the hexameric insulin-phenol complex,” Biophys. J. 95:4193-4204 (2008).
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